The Vistaar Project worked to provide capacity-building and technical assistance to help take knowledge to practice at large scale in major government programmes. The Project showed that selecting evidence-based and strategic approaches, like focusing on supporting the frontline worker, contributes to strong health outcomes. The Project also demonstrated that working closely with government priority programmes, focusing on systems improvements and strengthening existing platforms (such as training programmes and routine monthly meetings) yields strong results at scale and makes the results less dependent on Project inputs and more sustainable.